Over the last few months I’ve been getting involved in the informatics & data mining aspects of high content screening. While I haven’t gotten into image analysis itself (there’s a ton of good code and tools already out there), I’ve been focusing on managing image data and meta-data and asking interesting questions of the voluminuous, […]
MIOSS Workshop Wrap Up
The last few days I’ve been at the EBI, attending the Molecular Informatics Open Source Software (MIOSS) workshop. As part of this trip to the UK, I’ve also had the opportunity to present some of the work my colleagues and I have done at the NCTT – thanks to Mark Forster for the invitation to […]
ICCS 2011
A few openings are left for the International Conference on Chemical Structures (ICCS) A little less than 40 days left until the 9th International Conference on Chemical Structures (ICCS) starts in Noordwijkerhout, The Netherlands. The conference will focus on the latest scientific and technological developments in cheminformatics and related areas in six plenary sessions: o […]
Call for Papers: High Content Screening: Exploring Relationships Between Small Molecules and Phenotypic Results
242nd ACS National Meeting Denver, Aug 28 – Sept 1, 2011 CINF Division Dear Colleagues, we are organizing an ACS symposium, focusing on the use of High Content Screening (HCS) for small molecule applications. High content screens, while resource intensive, are capable of providing a detailed view of the phenotypic effects of small molecules. Traditional […]
Drug-Target Networks & Polypharmacology
I came across Takigawa et al where they address polypharmacology by investigating drug-target pairs. Their approach is to simultaneously identify substructures from the ligand and subsequences from the target and combine this information to suggest drug-target pairs that represent some form of polypharmacology. More specifically their hypothesis is that “polypharmacological principles” are embedded in a […]