The ONSChallenge has been running for some time now and the simple web query form that tied in the data from Google Docs along with web services from IU has turned out to be pretty handy. With more and more data becoming available, I had done some initial exploratory analysis of the measured solubilities. One […]
Combinatorial Libraries and Mixtures
Houghten, R. et al, “Strategies for the Use of Mixture-Based Synthetic Combinatorial Libraries: Scaffold Ranking, Direct Testing In Vivo, and Enhanced Deconvolution by Computational Methods”, J. Comb. Chem., 2008, 10, 3-19 Recently a collaborator pointed me to the above article by Houghten and co-workers where they describe the use of mixture-based combinatorial libraries for high-throughput […]