123. The NCATS BioPlanet — an integrated platform for exploring the universe of cellular signaling pathways for toxicology, systems biology, and chemical genomics
Huang, R.; Grishagin, I.; Wang, Y.; Zhao, T.; Greene, J.; Obenauer, J.C.; Nguyen, D.-T.; Guha, R.; Jadhav, A.; Southall, N.; Simeonov, A.; Austin, C.P.
2018, submitted
122. Target deconvolution of a multikinase inhibitor with anti-metastatic properties identifies TAOK3 as a key contributor to a cancer stemness phenotype
Biana, Y.; Tepera, Y.; Mathews-Greiner, L.A.; Aiken, T.J.; Shukla, V.; Guha, R.; Shin, P.; Xin, H.; Pflicke, H.; Powers, A.; Li, D.; Jiang, J.; Patel, P.; Rogers, S.A.; Aub, J.; Ferrer, M.; Thomas:, C.J.; Rudloff, U.
2018, submitted
121. PI3K/mTOR inhibition as a therapeutic strategy in FGFR4-driven rhabdomyosarcoma
McKinnon, T.; Venier, R.; Yohe, M.; Sindiri, S.; Gryder, B.; F., J.; Kabaroff, L.; Dickson, B.; Schleicher, K.; Chouinard-Pelletier, G.; Menezes, S.; Gupta, A.; Zhang, X.; Guha, R.; Ferrer, M.; Thomas, C.; Wei, Y.; Davani, D.; Guidos, C.; Khan, J.; Gladdy, R.
2018, submitted
120. High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer
Jansson, K.H.; Tucker, J.B.; Stahl, L.E.; Simmons, J.K.; Fuller, C.; Beshiri, M.L.; Agarwal, S.; Fang, L.; Hynes, P.G.; Alilin, A.N.; Lake, R.; Abbey, Y.; Cawley, J.; Tice, C.M.; Yin, J.J.; McKnight, C.; Klumpp-Thomas, C.; Zhang, X.; Guha, R.; Hoover, S.; Simpson, R.M.; Nguyen, H.M.; Corey, E.; Thomas, C.J.; Proia, D.A.; Kelly, A.K.
2018, submitted
119. High-throughput screen identifies HSP90 inhibitor efficacy across clinically-representative organoid models of advanced prostate cancer
Jansson, K.; Tucker, J.; Stahl, L.; Simmons, J.; Fuller, C.; Beshiri, M.; Agarwal, S.; Fang, L.; Hynes, P.; Alilin, A.; Cawley, J.; Lake, R.; Tran, C.; Tice, C.; Yin, J.; Zhang, X.; Guha, R.; Hoover, S.; Simpson, R.; Nguyen, H.; Corey, E.; Thomas, C.; Proia, D.; Kelly, K.
2018, submitted
118. High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma
Wang, S.; Hwang, E.E.; Guha, R.; O’Neill, A.F.; Melong, N.Veinotte.; Saur, A.C.; Shen, M.; McKnight, C.; Alexe, G.; Lemieux, M.E.; Wang, A.; Hughes, E.; Xu, X.; Boxer, M.B.; Hall, M.D.; Kung, A.; Berman, J.N.; Davis, M.I.; Stegmaier, K.; Crompton, B.D.
2018, submitted
117. A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation
Breglio, K.F.; Amato, R.; Eastman, R.; Lim, P.; Guha, R.; Ganesan, S.; Dorward, D.W.; Klumpp-Thomas, C.; McKnight, C.; Fairhurst, R.M.; Roberts, D.; Thomas, C.J.; Simon, A.K.
2018, submitted
116. The Assay Guidance Manual as a Public Resource: Quantitative Biology and Pharmacology in Preclinical Drug Discovery
Coussens, N.P.; Guha, R.; Pacifici, R.; Chin, B.; Arkin, M.; Auld, D.; Baell, J.; Bejcek, B.; Brimacombe, K.; Chung, T.D.; Dahlin, J.L.; Devanaryan, V.; Foley, T.L.; Gal-Edd, N.; Glicksman, M.; Grammer, S.; Grossman, A.; Hass, J.V.; Hoeppner, M.; Iversen, P.W.; Kahl, S.D.; Kales, S.C.; Lal-Nag, M.; Lathrop, S.; Lemmon, V.; Li, Z.; McGee, J.; McManus, O.; McVey, J.; Michael, S.; Minor, L.; Napper, A.; Riss, T.; Sayers, E.; Trask, O.J.; Trawick, B.; Weidner, J.R.; Wildey, M.J.; Xia, M.; Xu, X.; Knebel, A.; Hall, M.D.; Inglese, J.; Simeonov, A.; Austin, C.; Sittampalam, G.S.
Clin. Trans. Sci.,2018, in press
115. Resistance to epigenetic-targeted therapy engenders tumor cell vulnerabilities associated with enhancer remodeling
Iniguez, A.B.; Alexe, G.; Wang, E.J.; Roti, G.; Patel, S.; Chen, L.; Kitara, S.; Conway, A.; Stolte, B.; Bandopadhayay, P.; Goodale, A.; Hall, M.; Guha, R.; Cheff, D.; Davis, M.; Qi, J.; Beroukhim, R.; Piccioni, F.; Johannessen, C.; Stegmaier, K.
Cancer Cell,2018, in press
114. Identification of Combinations of Approved Drugs With Synergistic Activity Against Ebola Virus in Cell Cultures
Dyall, J.; Nelson, E.A.; DeWald, L.E.; Guha, R.; Hart, B.J.; Zhou, H.; Postnikova, E.; Logue, J.; Vargas, W.M.; Gross, R.; Michelotti, J.; Deiuliis, N.; Bennett, R.S.; Crozier, I.; Holbrook, M.R.; Morris, P.J.; Klumpp-Thomas, C.; McKnight, C.; Mierzwa, T.; Shinn, P.; Glass, P.J.; Johansen, L.; Jahrling, P.B.; Hensley, L.E.; Olinger, G.G.; Thomas, C.; White, J.M.
J. Infect. Disease,2018, in press
113. Combination of anthracyclines and anti-CD47 therapy inhibit invasive breast cancer growth while preventing cardiac toxicity by regulation of autophagy
Feliz-Mosquea, Y.; Christensen, A.; Cook, K.; Schwartz, A.; Chen, Q.R.; Griner-Mathews, L.; Guha, R.; Thomas, C.; Ferrer, M.; Merino, M.J.; Roberts, D.; Pantoja, D.S
Breast Cancer Res. Treat.,2018, in press
112. Pharmacological profiling and genomic characterization of human derived neurofibromatosis Type 1 plexiform neurofibroma-derived schwann cells
Ferrer, M.; Gosline, S.J.C.; Stathis, M.; Zhang, X.; Guo, X.; Guha, R.; Ryman, D.; Wallace, M.; Kasch-Semenza, L.; Hao, H.; Ashworth, R.; Ling, H.; Thomas, C.; Verma, S.; Guinney, J.; Blakeley, J.O.
Sci. Data,2018, 5(180106),
111. Characterization of Clinically Used Oral Antiseptics as Quadruplex-Binding Ligands
Calabrese, D.R.; Zlotkowski, K.; Alden, S.; Hewitt, W.M.; Connelly, C.M.; Wilson, R.M.; Gaikwad, S.; Chen, L.; Guha, R.; Thomas, C.J.; Mock, B.; Schneekloth, J.S.
Nucl. Acids Res.,2018, 46(6), 2722-2732
110. Functional Screening of FGFR4 Driven Tumorigenesis Identifies PI3K/mTOR Inhibition as an Effective Therapeutic Strategy in Rhabdomyosarcoma
McKinnon, T.; Venier, R.; Yohe, M.; Sindiri, S.; Gryder, B.; Shern, J.; Kabaroff, L.; Dickson, B.; Schleicher, K.; Chouinard-Pelletier, G.; Menezes, S.; Gupta, A.; Zhang, X.; Guha, R.; Ferrer, M.; Thomas, C.; Wei, Y.; Davani, D.; Guidos, C.; Khan, J.; Gladdy, R.A.
Oncogene,2018, 37(20), 2630-2644
109. Unexplored Therapeutic Opportunities in the Human Genome
Oprea, T.I.; Bologa, C.G.; Brunak, S.; Campbell, A.; Gan, G.N.; Gaulton, A.; Gomez, S.M.; Guha, R.; Hersey, A.; Holmes, J.; Jadhav, A.; Jensen, L.J.; Johnson, G.L.; Karlson, A.; Leach, A.R.; Ma’ayan, A.; Malovannaya, A.; Mani, S.; Mathias, S.L.; McManus, M.T.; Meehan, T.F.; Mering, C.V.; Nguyen, D.; Overington, J.P.; Papadatos, G.; Qin, J.; Reich, C.; Sch\”urer, S.C.; Simeonov, A.; Sklar, L.A.; Southall, N.; Tomita, S.; Tudose, I.; Ursu, O.; Vidovi\’c, D.; Waller, A.; Yang, J.J.; Zahoranszky-K\”ohalmi, G.
Nat. Rev. Drug Discov.,2018, 17, 317-332
108. A systematic and prospectively validated approach for identifying synergistic drug combinations against malaria
Kalantat-Motamedi, Y.; Eastman, R.T.; Guha, R.; Bender, A.
Malaria J.,2018, 17(160), 1-15
107. MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma
Yohe, M.E.; Gryder, B.E.; Shern, J.F.; Chou, H.C.; Song, Y.K.; Liao, H.; Sindiri, S.; Mendoza, A.; Zhang, X.; Guha, R.; Haines, D.C.; Mathews-Griner, L.A.; Li, S.Q.; Ferrer, M.; Thomas, C.J.; Khan, J.
Sci. Transl. Med.,2018, 10(448), eaan4470
106. Encouraging and enabling research on under- and unstudied targets
Guha, R.; Simeonov, A.
Drug Target Review,2018, 1, 1-5
105. Using Machine Learning to Predict Synergistic Antimalarial Compound Combinations with Novel Structures
Mason, D.J.; Eastman, R.T.; Lewis, R.P.I.; Stott, I.P.; Guha, R.; Bender, A.
Frontiers in Pharmacology,2018, ,
104. Targeting resistance mechanisms to CDK4/6 inhibitors with an IGFR inhibitor drug combination strategy
Guenther, L.M.; Dharia, N.V.; Ross, L.; Convway, A.; Robichaud, A.L.; Frank, E.S.; Catlett, J.L.; Wechsler, C.; Goodale, A.; Church, A.; Tseng, Y.Y.; Guha, R.; McKnight, C.; Janeway, K.A.; Mora, J.; Davis, M.I.; Alexe, G.; Piccioni, F.; Stegmaier, K.
Clin. Cancer. Res,2018, ,
103. Mutation Profiles in Glioblastoma 3D Oncospheres Modulate Drug Efficacy
Wilson, K.M.; Mathews-Greiner, L.A.; Williamson, T.; Guha, R.; Keller, J.M.; Shinn, P.; McKnight, C.; Michael, S.; Klumpp-Thomas, C.; Chen, L.; Binder, Z.A.; Ferrer, M.; Gallia, G.L.; Thomas, C.J.; Riggins, G.J.
SLAS Tech.,2018, ,
102. Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening
Lee, O.W.; Austin, S.; Cheff, D.M.; Lee, T.D.; Wilson, K.M.; Johnson, J.; Travers, J.; Braisted, J.C.; Guha, R.; Klump-Thomas, C.; Shen, M.; Hall, M.
2018, (submitted),
101. Canvass: a crowd-sourced, natural product screening library for exploring biological space
Kearney, S.E.; Zahornszky-Khalmi, G.; Brimacombe, K.R.; Henderson, M.J.; Lynch, C.; Zhao, T.; Wan, K.K.; Itkin, Z.; Dillon, C.; Shen, M.; Cheff, D.M.; Lee, T.D.; Bougie, D.; Cheng, K.; Coussens, N.P.; Dorjsuren, D.; Eastman, R.T.; Huang, R.; Iannotti, M.J.; Karavadhi, S.; Klumpp-Thomas, C.; Roth, J.S.; Sakamuru, S.; Sun, W.; Titus, S.A.; Yasgar, A.; Zhang, Y.; Zhao, J.; Andrade, R.B.; Brown, M.K.; Burns, N.Z.; Cha, J.K.; Mevers, E.E.; Clardy, J.; Clement, J.A.; Crooks, P.A.; Cuny, G.D.; Ganor, J.; Moreno, J.; Morril, L.A.; Picazo, E.; Susick, R.B.; Garg, N.K.; Goess, B.C.; Grossma, R.B.; Hughes, C.C.; Johnston, J.N.; Joullie, M.M.; Kinghorn, A.D.; Kingston, D.G.; Krische, M.J.; Kwon, O.; Maimone, T.J.; Majumdar, S.; Maloney, K.N.; Mohamed, E.; Murphy, B.T.; Nagorny, P.; Olson, D.E.; Overman, L.E.; Brown, L.E.; Snyder, J.K.; Porc, J.A.; Jr, ..; Rivas, F.; Ross, S.A.; Sarpong, R.; Sharma, I.; Shaw, J.T.; Xu, Z.; Shen, B.; Shi, W.; Stephenson, C.R.; Verano, A.L.; Tan, D.S.; Tang, Y.; Taylor, R.E.; Thomson, R.J.; Vosburg, D.A.; Wu, J.; Wuest, W.M.; Zakarian, A.; Zhang, Y.; Ren, T.; Zuo, Z.; Inglese, J.; Michael, S.; Simeonov, A.; Zheng, W.; Shinn, P.; Jadhav, A.; Boxer, M.B.; Hall, M.D.; Xia, M.; Guha, R.; Rohde, J.M.
submitted,2018, ,
100. The rise and fall of a scaffold: A trend analysis of scaffolds in the medicinal chemistry literature
Zdrazil, B.; Guha, R.
J. Med. Chem.,2017, in press
99. The Chemistry Development Kit (CDK): atom typing, rendering, molecular formulas, and substructure searching
Willighagen, E.L.; May, J.W.; Alvarsson, J.; Berg, A.; Carlsson, L.; Duhrkop, K.; Jeliazkova, N.; Kuhn, S.; Pluskal, T.; Rojas-Cherto, M.; Spjuth, O.; Torrance, G.; Evelo, C.T.; Guha, R.; Steinbeck, C.
J. Cheminf.,2017, 9(33),
98. Helping to improve the practice of cheminformatics
Guha, R.; Willighagen, E.L.
J. Cheminf.,2017, 9(40),
97. Drug Target Ontology to Classify and Integrate Drug Discovery Data
Lin, Y.; Mehta, S.; McGinty, H.K.; Turner, J.P.; Vidovic, D.; Forlin, M.; Koleti, A.; Nguyen, D.-T.; Jensen, L.J.; Guha, R.; Mathias, S.; Ursu, O.; Stathias, V.; Duan, J.; Nabizadeh, N.; Chung, C.; Mader, C.; Visser, U.; Yang, J.Bologa.; Oprea, T.I.; Sch\”urer, S.C.
J. Biomed. Semantics,2017, 8(50),
96. PAX3-FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability
Gryder, B.E.; Yohe, M.E.; Chou, H.C.; Zhang, X.; Song, Y.; Marques, J.; Schaefer, B.; Sen, N.; Patidar, R.; Wen, X.; Wei, J.; Guha, R.; Ferrer, M.; Lal-Nag, M.; Andresson, T.; Shern, J.F.; Zhao, K.; Thomas, C.J.; Khan, J.
Cancer Discov.,2017, 7(8), 884-899
95. Pharos: Collating Protein Information to Shed Light on the Druggable Genome
Nguyen, D.-T.; Mathias, S.; Bologa, C.; Brunak, S.; Fernandez, N.; Gaulton, A.; Hersey, A.; Holmes, J.; Jensen, L.J.; Karlsson, A.; Lu, G.; Mayan, A.; Mandava, G.; Mani, S.; Mehta, S.; Overington, J.P.; Patel, J.; Rouillard, A.D.; Schurer, S.; Sheils, T.; Simeonov, A.; Sklar, L.; Southall, N.; Ursu, O.; Vidovic, D.; Waller, A.; J., Y.; Jadhav, A.; Oprea, T.I.; Guha, R.
Nucl. Acids Res.,2017, 45(D1), D995-D1002
94. Matrix screen identifies synergistic combination of PARP inhibitors and nicotinamide phosphoribosyltransferase (NAMPT) inhibitors in Ewing sarcoma
Heske, C.; Davis, M.; Baumgart, J.; Wilson, K.; Gormally, M.; Chen, L.; Zhang, X.; Ceribelli, M.; Duveau, D.; Guha, R.; Ferrer, M.; Arnaldez, F.; Ji, J.; Tran, H.; Zhang, Y.; Mendoza, A.; Helman, L.; Thomas, C.
Clin. Cancer. Res,2017, 23(23), 7301-7311
93. Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer
Chen, I.; Mathews-Greiner, L.; Li, D.; Abisoye-Ogunniyan, A.; Ray, S.; Bian, Y.; Shukla, V.; Zhang, X.; Guha, R.; Thomas, C.; Gryder, B.; Zacharia, A.; Beane, J.D.; Ravichandran, S.; Ferrer, M.; Rudloff, U.
J. Translat. Med.,2017, 15(1), 92
92. The Phosphatidylinositol-3-phosphate 5-kinase Inhibitor Apilimod Blocks Filoviral Entry and Infection
Nelson, E.A.; Dyall, J.; Hoenen, T.; Barnes, A.B.; Zhou, H.; Liang, J.Y.; Michelotti, J.; Dewey, W.H.; DeWald, L.E.; Bennett, R.S.; Morris, P.J.; Guha, R.; Klumpp-Thomas, C.; McKnight, C.; Chen, Y.; Xu, X.; Wang, A.; Hughes, E.; Martin, S.; Thomas, C.; Jahrling, P.B.; Hensley, L.E.; Olinger, G.G.; White, J.M.
PLoS Neglected Trop. Dis.,2017, 11(4), 1-22
91. Cancer network activity associated with therapeutic response and synergism
Serra-Musach, J.; Mateo, F.; Capdevila-Busquets, E.; Zhang, X.; Guha, R.; Thomas, C.; Gruseo, J.; Ruiz de Garibay, G.; Villaneuva, A.; Gustafsson, M.; Benson, M.; Jaeger, S.; Heyn, H.; Vizoso, M.; Perez, H.; Cordero, A.; Gonzalez-Suarez, E.; Esteller, M.; Moreno-Bueno, G.; Lazaro, C.; Serra, V.; Arribas, J.; Ferrer, M.; Aloy, P.; Pujana, M.A.
Genome Medicine,2016, 8(1), 1-12
90. Large Scale Pharmacological Profiling of 3D Tumor Models of Cancer Cells
Mathews-Griner, L.A.; Zhang, X.; Guha, R.; McKnight, C.; Goldlust, I.S.; Lal, M.; Wilson, K.; Michael, S.; Titus, S.; Shinn, P.; Thomas, C.; Ferrer, M.
Cell Death & Disease,2016, 7(12), e2492
89. Large Scale Screening and Identification of Novel Ebolavirus and Marburgvirus Entry Inhibitors
Anantpadma, M.; Kouznetsova, J.; Wang, H.; Huang, R.; Guha, R.; Lindstrom, A.; Shtanko, O.; Simeonov, A.; Maloney, D.J.; Maury, W.; LaCount, D.; Jadhav, A.; Davey, R.
Antimicrobial Agents and Chemotherapy,2016, 60(8), 4471-4481
88. mQC: A Heuristic Quality-Control Metric for High-Throughput Drug Combination Screening
Chen, L.; Wilson, K.; Goldlust, I.S.; Mott, B.T.; Eastman, R.T.; Davis, M.I.; Zhang, X.; McKnight, C.; Klumpp-Thomas, C.; Shinn, P.; Simmons, J.; Gormally, M.; Michael, S.; Thomas, C.J.; Ferrer, M.; Guha, R.
Sci. Rep.,2016, 6(37741), 1
87. A druggable TCF4- and BRD4-dependent transcriptional network sustains malignancy in blastic plasmacytoid dendritic cell neoplasm
Ceribelli, M.; Kelly, P.N.; Ganapathi, K.; Evbuomwan, M.; Stefania, P.; Shaffer, A.L.; Wright, G.; Xiao, W.; Guha, R.; Zhang, X.; Ferrer, M.; Hou, E.Z.; Jaffe, E.S.; Reizis, B.; Thomas, C.; Staudt, L.M.
Cancer Cell,2016, 30, 764-778
86. A high throughput screening model of the tumor microenvironment for ovarian cancer cell growth
Lal-Nag, M.; McGee, L.; Guha, R.; Lengyel, E.; Kenny, H.A.; Ferrer, M.
SLAS Discovery,2016, 22(5), 494-506
85. Ranking Differential Drug Activities from Dose Response Synthetic Lethality Screens
Guha, R.; Mathews-Griner, L.A.; Keller, J.; Fitzgerald, D.J.; Atignani, A.; Pastan, I.; Thomas, C.J.; Ferrer, M.
J. Biomol. Screen.,2016, 21(9), 942-955
84. RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription
Baranello, L.; Wojtowicz, D.; Kouzine, F.; Cui, K.; Chan-Salis, K.Y.; Devaiah, B.; Wilson, K.; Guha, R.; Thomas, C.; Singer, D.; Pommier, Y.; Pugh, B.F.; Przytyka, T.M.; Lewis, B.A.; Zhao, K.; Levens, D.
Cell,2016, 165(2), 357-371
83. Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond
Van Voorhis, W.C. et al
PLoS Pathogens,2016, 12(7), e1005763
82. Augmented efficacy of brentuximab vedotin combined with ruxolitinib and/or Navitoclax in a murine model of human Hodgkin’s Lymphoma
Jun, W.; Zhang, M.; Wilson, K.; Petrus, M.N.; Bamford, R.; Zhang, X.; Guha, R.; Ferrer, M.; Thomas, C.; Waldmann, T.A.
Proc. Nat. Acad. Sci.,2016, 113(6), 1624-1629
81. Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus In Vitro and In Vivo
Cong, Y.; Dyall, J.; Hart, B.J.; DeWald, L.E.; Johnson, J.C.; Postnikova, E.; Zhou, H.; Gross, R.; Rojas, O.; Alexander, I.; Josleyn, N.; Zhang, T.; Michelotti, J.; Janosko, K.; Honko, A.; Holbrook, M.; Bennett, R.S.; Olinger, G.O.; Glass, P.J.; Thomas, C.; Mierzwa, T.; Guha, R.; Shinn, P.; Michael, S.; Klumpp-Thomas, K.; McKnight, C.; Hensley, L.; Jahrling, P.B.
PLoS One,2016, 11(11), e0166318
80. Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-toxin fusion proteins
Antignani, A.; Mathews Griner, L.; Guha, R.; Simmon, N.; Pasetto, M.; Keller, J.; Huang, M.; Angelus, E.; Pastan, I.; Ferrer, M.; FitzGerald, D.; Thomas, C.
PLoS One,2016, 11(8), e0161415
79. Actinoramide A stereoisomer identified as potent anti-malarial from titration-based screening of marine natural product extracts
Cheng, K.Chih-Chien.; Cao, S.; Raveh, A.; MacArthur, R.; Dranchak, P.; Chlipala, G.; Okoneski, M.T.; Guha, R.; Eastman, R.T.; Yuan, J.; Schultz, P.J.; Su, X.; Tamayo-Castillo, G.; Matainaho, T.; Clardy, J.; Sherman, D.H.; Inglese, J.
J. Nat. Prod.,2015, 78(10), 2411-2422
78. Synergy Maps: Exploring compound combinations using network-based visualization
Lewis, R.; Guha, R.; Korcsmaros, T.; Bender, A.
J. Cheminf.,2015, 7(36),
77. Aurora B Kinase is a Potent and Selective Target in MYCN-driven Neuroblastoma
Bogen, D.; Wei, J.S.; Azorsa, D.O.; Ormanoglu, P.; Buehler, E.; Guha, R.; Keller, J.M.; Mathews-Griner, L.A.; Ferrer, M.; Song, Y.K.; Liao, H.; Mendoza, A.; Gryder, B.E.; Sindri, S.; He, J.; Wen, X.; Zhang, S.; Shern, J.F.; Yohe, M.E.; Taschner-Mandl, S.; Shohet, J.M.; Thomas, C.J.; Martin, S.E.; Ambros, P.F.; Khan, J.
Oncotarget,2015, 6(34), 35247-35262
76. High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations
Mott, B.T.; Eastman, R.T.; Guha, R.; Sherlach, K.S.; Siriwardana, A.; Shinn, P.; McKnight, C.; Michael, S.; Lacerda-Quieroz, N.; Patel, P.R.; Khine, P.; Sun, H.; Kasbeka, M.; Aghdam, N.; Fontaine, S.D.; Liu, D.; Mierzwa, T.; Mathews-Griner, L.A.; Ferrer, M.; Renslo, A.R.; Inglese, J.; Yuan, J.; Roepe, P.D.; Su, X.; Thomas, C.J.
Scientific Reports,2015, 5(13891),
75. MP68-17 Novel Intravesical Therapies Identified from High Throughput Screening
Lewi, K.; Nair, A.; Railkar, R.; Brancato, S.; Hsu, I.; Li, Q.; Zhang, X.; Guha, R.; Apolo, A.; Theodorescu, D.
J. Urology,2015, 193(4), e864-e865
74. Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia
Zhang, M.; Mathews-Griner, L.A.; Ju, W.; Duveau, D.; Guha, R.; Petrus, M.N.; Wen, B.; Maeda, M.; Shinn, P.; Ferrer, M.; Conlon, K.D.; Bamford, R.; Oshea, J.; Thomas, C.J.; Waldmann, T.A.
Proc. Nat. Acad. Sci.,2015, 112(40), 12480-12485
73. A whole genome RNAi screen highlights components of the ER/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity
Pasetto, M.; Antignani, A.; Ormanoglu, P.; Buehler, E.; Guha, R.; Pastan, I.; Fitzgerald, D.J.
Proc. Nat. Acad. Sci.,2015, 112(10), 1135-1142
72. Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays
Lee, J.A.; Shinn, P.; Jaken, S.; Oliver, S.; Willard, F.S.; Heidler, S.; Peery, R.B.; Oler, J.; Chu, S.; Southall, N.; Dexheimer, T.S.; Smallwood, J.; Huang, R.; Guha, R.; Jadhav, A.; Cox, K.; Austin, C.P.; Simeonov, A.; Sittampalam, G.Sitta.; Husain, S.; Franklin, N.; Wild, D.J.; Yang, J.J.; Sutherland, J.J.; Thomas, C.J.
PLoS ONE,2015, 10(7), e0130796 EP –
71. Chemogenomic profiling of endogenous PARK2 expression using a genome-edited coincidence reporter
Hasson, S.; Fogel, A.I.; Wang, C.; MacArthur, R.; Guha, R.; Heman-Ackah, S.; Martin, S.E.; Youle, R.J.; Inglese, J.
ACS Chem. Biol.,2015, 10(5), 1188-1197
70. Modelling of compound combination effects and applications to efficacy and toxicity: state-of-the-art, challenges and perspectives
Bulusu, K.C.; Guha, R.; Mason, D.J.; Lewis, R.; Muratov, E.; Kalantat-Motamedi, Y.; Cokol, M.; Bender, A.
Drug. Discov. Today,2015, ,
69. Evaluating disease similarity using latent dirichlet allocation
Frick, J.M.; Guha, R.; Peryea, T.; Southall, N.T.
bioRxiv,2015, ,
68. A high-throughput assay for small molecule destabilizers of the KRAS oncoprotein
Carver, J.; Dexheimer, T.S.; Hsu, D.; Weng, M.T.; Guha, R.; Jadhav, A.; Simeonov, A.; Luo, J.
PLoS One,2014, 9(8), e103836
67. Genome editing-enabled HTS assays expand drug target pathways for Charcot-Marie-Tooth disease
Inglese, J.; Dranchak, P.; Moran, P.; Jang, S.-W.; Cost, G.J.; Srinivasan, R.; Guha, R.; Martinez, N.; MacArthur, R.; Urnov, F.D.; Svaren, J.
ACS Chem. Biol.,2014, 9(11), 2594-2602
66. ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase I inhibitors by disabling DNA replication initiation and fork elongation responses
Josse, R.; S.E., M.; Guha, R.; Ormanoglu, P.; Pfister, T.; Morris, J.; Doroshow, J.; Pommier, Y.
Cancer. Res.,2014, 74(23), 6968-6979
65. On the Validity versus Utility of Activity Landscapes: Are All Activity Cliffs Statistically Significant?
Guha, R.; Medina-Franco, J.L.
J. Cheminf.,2014, 6(11),
64. BioAssay Research Database (BARD): Chemical biology and probe-development enabled by structured metadata and result types
Howe, E.; de Souza, A.; Lahr, D.; Chatwin, S.; Montgomery, P.; Alexander, B.; Nguyen, D.-T.; Cruz, Y.; Stonish, D.; Walzer, G.; Jason, R.; Picard, S.; Liu, Z.; Rose, J.; Xiang, X.; Asiedu, J.; Durkin, D.; Levine, J.; Yang, J.; Sch\”urer, S.; Braisted, J.; Southall, N.; Southern, M.; Chung, T.D.Y.; Brudz, S.; Tanega, C.; Schreiber, S.L.; Bittker, J.; Guha, R.; Clemons, P.
Nucl. Acids Res.,2014, 43, D1163-D1170
63. An overview of the challenges in designing, integrating, and delivering BARD: A public chemical-biology resource and query portal for multiple organizations, locations, and disciplines
de Souza, A.; Bittker, J.; Lahr, D.; Brudz, S.; Chatwin, S.; Oprea, T.I.; Waller, A.; Yang, A.; Southall, N.; Guha, R.; Schurer, S.; Vempati, U.; Southern, M.R.; Dawson, E.S.; Clemons, P.A.; Chung, T.D.Y.
J. Biomol. Screen.,2014, 19(5), 614-627
62. Blockade of oncogenic I$\kappa$B kinase activity in ABC DLBCL by small molecule BET protein inhibitors
Ceribelli, M.; Priscilla, K.; Shaffer, A.L.; Wright, G.; Yang, Y.; Mathews-Griner, L.A.; Guha, R.; Shinn, P.; Keller, J.M.; Liu, D.; Patel, P.R.; Ferrer, M.; Joshi, S.; Nerle, S.; Sandy, P.; Normant, E.; Thomas, C.J.; Staudt, L.M.
Proc. Natl. Acad. Sci.,2014, 111(31), 11365-11370
61. High-throughput combinatorial screening identifies drugs that cooperate with Ibrutinib to kill ABC Diffuse Large B Cell Lymphoma cells
Mathews, L.; Guha, R.; Shinn, P.; Young, R.A.; Keller, J.; Liu, D.; Goldlust, I.S.; Yasgar, A.; McKnight, C.; Boxer, M.B.; Duveau, D.; Jiang, J.K.; Michael, S.; Mierzwa, T.; Huang, W.; Walsh, M.J.; Mott, B.T.; Patel, P.R.; Leister, W.; Maloney, D.J.; LeClair, C.A.; Rai, G.; Jadhav, A.; Peyser, B.D.; Austin, C.P.; Martin, S.; Simeonov, A.; Ferrer, M.; Staudt, L.M.; Thomas, C.J.
Proc. Nat. Acad. Sci.,2014, 111(6), 2349-2354
60. Inhibition of Ceramide Metabolism Sensitizes Human Leukemia Cells to Inhibition of BCL2-like Proteins
Casson, L.; Howell, L.; Mathews, L.A.; Ferrer, M.; Southall, N.; Guha, R.; Keller, J.M.; Thomas, C.; Varmus, H.; Siskind, L.J.; Beverly, L.J.
PLoS One,2013, 8, e54525
59. Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: Implications for reporter-gene assays
Dranchak, P.; MacArthur, R.; Guha, R.; Zuercher, W.J.; Drewry, D.H.; Auld, D.S.; Inglese, J.
PLoS One,2013, 8(3),
58. Genome-wide high-content RNAi screens identify regulators of Parkin upstream of mitophagy
Hasson, S.; Kane, L.; Sliter, D.; Hessa, T.; Wang, C.; Buehler, E.; Guha, R.; Martin, S.; Yamano, K.; Huang, C.H.; Heman-Ackah, S.; Youle, R.
Nature,2013, 504, 291-295
57. What are we “tweeting” About Obesity? Mapping Tweets with Topic Modeling and Geographic Information System
Ghosh, D.; Guha, R.
Cartography and GIS,2013, 4(2), 90-102
56. RNAi Screen Reveals Candidate miRNAs Associated with the NF-kappaB Pathway
Redan, B.W.; Motobar, O.; Tuzmen, P.; Guha, R.; Caplen, N.J.; S.E., M.
FASEB J.,2013, 27, 780-781
55. Targeting IRAK1 as a Novel Therapeutic Approach for Myelodysplastic Syndrome
Rhyasen, G.W.; Bolanos, L.; Fang, J.; Rasch, C.; Jerez, A.; Varney, M.; Wunderlicj, M.; Rigolino, C.; Mathews, L.; Ferrer, M.; Southall, N.; Guha, R.; Keller, J.; Thomas, C.; Beverly, L.J.; Agostino, C.; Oliva, E.N.; Cuzzola, M.; Maciejewski, J.P.; Mulloy, J.C.; Starczynowski, D.T.
Cancer Cell,2013, 24(1), 90-104
54. Large-Scale Screening Identifies a Novel microRNA, miR-15a-3p, which Induces Apoptosis in Human Cancer Cell Lines
Druz, A.; Chen, Y.C.; Guha, R.; Betenbaugh, M.; Martin, S.; Shiloaoch, J.
RNAi Biology,2013, 10(2), 1-14
53. Cisplatin Sensitivity Mediated by WEE1 and CHK1 is Mediated by miR-155 and the miR-15 Family
Pouliot, L.M.; Chen, Y.-C.; Bai, J.; Guha, R.; Martin, S.E.; Gottesman, M.M.; Hall, M.D.
Cancer Cell,2012, 72(22), 5945-5955
52. Identification of Mammalian Protein Quality Control Factors by High-throughput Cellular Imaging
Pegoraro, G.; Voss, T.C.; Martin, S.E.; Tuzmen, P.; Guha, R.; Mistelli, T.
PLoS One,2012, 7(2), e31684
51. High-Throughput Screening For Genes That Prevent Excess DNA Replication In Human Cells And For Molecules That Inhibit Them
Lee, C.; Johnson, R.L.; Wichterman-Kouznetsova, J.; Guha, R.; Ferrer, M.; Tuzmen, P.; Martin, S.; Zhu, W.; Depamphilis, M.L.
Methods,2012, 57(2), 234-248
50. Cheminformatics, the Computer Science of Chemical Discovery Turning Open Source
Sterling, A.; Wegner, J.K.; Guha, R.; Bender, A.; Faulon, J.; Hastings, J.; O’Boyle, N.; Overington, J.P.; Vlijmen, H.V.; Willighagen, E.
Comm. ACM,2012, 55(11), 65-75
49. Exploring Uncharted Territories — Predicting Activty Cliffs in Structure-Activity Landscapes
Guha, R.
J. Chem. Inf. Model.,2012, 52(8), 2181-2191
48. Dealing with the Data Deluge: Handling the Multitude of Chemical Biology Data Sources
Guha, R.; Nguyen, D.-T.; Southall, N.; Jadhav, A.
Curr. Protocols Chem. Biol.,2012, 4, 193-209
47. A Furoxan-Amodiaquine Hybrid as a Potential Therapeutic for Three Parasitic Diseases
Mott, B.T.; Cheng, C.C.; Guha, R.; Kommer, V.P.; Williams, D.L.; Vermeire, J.J.; Cappello, M.; Maloney, D.J.; Rai, G.; Jadhav, A.; Simeonov, A.; Inglese, J.; Posner, G.H; Thomas, C.J.
Med. Chem. Comm.,2012, 3, 1505-1511
46. Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria
Heidebrecht, R.W.; Mulrooney, C.; Austin, C.P.; Barker, R.H.; Beaudoin, J.A.; Cheng, K.Chih-Chien.; Comer, E.; Dandapani, S.; Dick, J.; Duvall, J.R.; Ekland, E.H.; Fidock, D.A.; Fitzgerald, M.E.; Foley, M.; Guha, R.; Hinkson, P.; Kramer, M.; Lukens, A.K.; Masi, D.; Marcaurelle, L.A.; Su, X.; Thomas, C.J.; Wewer, M.; Wiegand, R.C.; Wirth, D.; Xia, M.; Yuan, J.; Zhao, J.; Palmer, M.; Munoz, B.; Schreiber, S.
ACS Med. Chem. Lett.,2012, 3(2), 112-117
45. Exploiting Synthetic Lethality for the Therapy of ABC Diffuse Large B Cell Lymphoma
Yang, Y.; Shaffer, A.; Emre, N. C. ?Tolga; Ceribelli, M.; Zhang, M.; Wright, G.; Xiao, W.; Powell, J.; Platig, J.; Kohlhammer, H.; Young, R.; Zhao, H.; Yang, Y.; Xu, W.; Buggy, J.; Balasubramanian, S.; Mathews, L.; Shinn, P.; Guha, R.; Ferrer, M.; Thomas, C.; Waldmann, T.; Staudt, L.
Cancer Cell,2012, 21(6), 723-737
44. Exploring Structure-Activity Data Using the Landscape Paradigm
Guha, R.
WIREs Comput. Mol. Sci.,2012, 2(6), 829-841
43. A 1536-well Quantitative High Throughput Screen to Identify Compounds Targeting Cancer Stem Cells
Mathews, L.A.; Keller, J.M.; Goodwin, B.; Guha, R.; Shinn, P.; Mull, R.; Thomas, C.; de Kluyver, R.; Sayers, T.; Ferrer, M.
J. Biomol. Screen.,2012, 17(9), 1231-1242
42. A Survey of Quantitative Descriptions of Molecular Structure
Guha, R.; Willighagen, E.L.
Curr. Topics Med. Chem.,2012, 12(18), 1946-1956
41. Genome-Wide RNAi Screen For Lysosomal Storage Disorders
Velayati, A.; Tuzmen, P.; Guha, R.; Martin, S.; Goldin, E.; Sidransky, E.
Molecular Genetics and Metabolism,2012, 105(2), S63
40. Chemical Genomic Profiling for Antimalarial Therapies, Response Signatures, and Molecular Targets
Yuan, J.; Cheng, K.Chih-Chien.; Johnson, R.L.; Huang, R.; Pattaradilokrat, S.; Liu, A.; Guha, R.; Fidock, D.A.; Inglese, J.; Wellems, T.E.; Austin, C.P.; Su, X.
Science,2011, 333(6043), 724-729
39. KNIME workflow to assess PAINS filters in SMARTS format. Comparison of RDKit and Indigo cheminformatics libraries
Saubern, S.; Guha, R.; Baell, J.B.
Mol. Inf.,2011, 30(10), 847-850
38. Open Data, Open Source and Open Standards in Chemistry: The Blue Obelisk Five Years On
O’Boyle, N.; Guha, R.; Willighagen, E.; Adams, S.E.; Alvarsson, J.; Bradley, J.C.; Filippov, I.; Hanson, R.M.; Hanwell, M.D.; Hutchison, G.R.; James, C.A.; Jeliazkova, N.; Lang, A.; Langner, K.M.; Lonie, D.C.; Lowe, D.M.; Pansanel, J.; Pavlov, D.; Spjuth, O.; Steinbeck, C.; Tenderholt, A.; Theisen, K.; Murray-Rust, P.
J. Cheminf.,2011, 3(37),
37. Exploratory analysis of kinetic solubility measurements of a small molecule library
Guha, R.; Dexheimer, T.S.; Kestranek, A.N.; Jadhav, A.; Chervenak, A.M.; Ford, M.G.; Simeonov, A.; Roth, G.P.; Thomas, C.J.
Bioorg. Med. Chem.,2011, 19(13), 4127-4134
36. RNAi Screening Identifies TAK1 as a Potential Target for the Enhanced Efficacy of Topoisomerase Inhibitors
Martin, S.E.; Wu, Z.H.; Gehlhaus, K.Jones.; Zhang, Y.W.; Guha, R.; Miyamoto, S.; Pommier, Y.; Caplen, N.J.
Curr. Cancer Drug Targets,2011, 11(8), 976-986
35. Improving Usability and Accessibility of Cheminformatics Tools for Chemists Through Cyberinfrastructure and Education
Guha, R.; Wiggins, G.D.; Wild, D.J.; Baik, M.H.; Pierce, M.E.; Fox, G.C.
In Silico Biol.,2011, 11(1–2), 41-60
34. Discovery of New Antimalarial Chemotypes Through Chemical Methodology and Library Development
Brown, L.E.; Chih-Chien Cheng, K.; Wei, W.; Yuan, P.; Dai, P.; Trilles, R.; Ni, F.; Yuan, J.; MacArthur, R.; Guha, R.; Johnson, R.L.; Su, X.; Dominguez, M.M.; Snyder, J.K.; Beeler, A.B.; Schaus, S.E.; Inglese, J.; Porco, J.
Proc. Nat. Acad. Sci.,2011, 108(17), 6775-6780
33. Advances in Cheminformatics Methodologies and Infrastructure to Support the Data Mining of Large, Heterogeneous Chemical Datasets
Guha, R.; Gilbert, K.; Fox, G.C.; Pierce, M.; Wild, D.; Yuan, H.
Curr. Comp. Aid. Drug Des.,2010, 6(1), 50-67
32. Use of Genetic Algorithm and Neural Network Approaches for Risk Factor Selection: A Case Study of West Nile Virus Dynamics in an Urban Environment
Ghosh, D.; Guha, R.
Computers, Environment and Urban Systems,2010, 34(3), 189-203
31. Towards interoperable and reproducible QSAR analyses: Exchange of datasets.
Spjuth, O.; Willighagen, E.L.; Guha, R.; Eklund, M.; Wikberg, J.
Journal of Cheminformatics,2010, 2(1),
30. PubChem as a Source of Polypharmacology
Chen, B.; Wild, D.; Guha, R.
J. Chem. Inf. Model.,2009, 49(9), 2044-2055
29. Chemoinformatic Analysis of Drugs, Natural Products, Molecular Libraries Small Molecule Repository and Combinatorial Libraries
Singh, N.; Guha, R.; Guilianotti, M.; Houghten, R.; Medina-Franco, J.L.
J. Chem. Inf. Model.,2009, 49(4), 1010-1024
28. Navigating Structure Activity Landscapes
Bajorath, J.; Peltason, L.; Wawer, M.; Guha, R.; Lajiness, M.S.; van Drie, J.H.
Drug Discov. Today,2009, 14(13–14), 698-705
27. Pharmacophore Representation and Searching
Guha, R.; Van Drie, J.H.
CDK News,2008, ASAP
26. Assessing how well a modeling protocol captures a structure-activity landscape
Guha, R.; Van Drie, J.H.
J. Chem. Inf. Model.,2008, 48(8), 1716-1728
25. The Structure-Activity Landscape Index: Identifying and Quantifying Activity-Cliffs
Guha, R.; Van Drie, J.H.
J. Chem. Inf. Model.,2008, 48(3), 646-658
24. A Flexible Web Service Infrastructure for the Development and Deployment of Predictive Models
Guha, R.
J. Chem. Inf. Model.,2008, 48(2), 456-464
23. On the Interpretation and Interpretability of QSAR Models
Guha, R.
J. Comp. Aid. Molec. Des.,2008, 22(12), 857-871
22. Utilizing high throughput screening data for predictive toxicology models: Protocols and application to MLSCN assays
Guha, R.; Sch\”urer, S.C.
J. Comp. Aid. Molec. Des.,2008, 22(6–7), 367-384
21. Userscripts for the Life Sciences
Willighagen, E.L.; O’Boyle, N.; Gopalakrishnan, H.; Jiao, D.; Guha, R.; Steinbeck, C.; Wild, D.J.
BMC Bioinformatics,2007, 8, 487
20. Chemical Data Mining of the NCI Human Tumor Cell Line Database
Wang, H.; Klinginsmith, J.; Dong, X.; Lee, A.; Guha, R.; Wu, Y.; Crippen, G.; Wild, D.J.
J. Chem. Inf. Model.,2007, 47(6), 2063-2076
19. Counting Clusters Using R-NN Curves
Guha, R.; Dutta, D.; Chen, T.; Wild, D.J.
J. Chem. Inf. Model.,2007, 47(4), 1308-1318
18. A Web Service Infrastructure for Chemoinformatics
Dong, X.; Gilbert, K.; Guha, R.; Heiland, R.; Kim, J.; Pierce, M.; Fox, G.; Wild, D.J.
J. Chem. Inf. Model.,2007, 47(4), 1303-1307
17. Ensemble Feature Selection: Consistent Descriptor Subsets for Multiple QSAR Models
Dutta, D.; Guha, R.; Chen, T.; Wild, D.J.
J. Chem. Inf. Model.,2007, 47(3), 989-997
16. Chemical Informatics Functionality in R
Guha, R.
J. Stat. Soft.,2007, 18(6),
15. Local Lazy Regression: Making Use of the Neighborhood to Improve QSAR Predictions.
Guha, R.; Dutta, D.; Jurs, P.C.; Chen, T.
J. Chem. Inf. Model.,2006, 46(4), 1836-1847
14. R-NN Curves: An Intuitive Approach to Outlier Detection Using a Distance Based Method
Guha, R.; Dutta, D.; Jurs, P.C; Chen, T.
J. Chem. Inf. Model.,2006, 46(4), 1713-1722
13. The Blue Obelisk–Interoperability in Chemical Informatics.
Guha, R.; Howard, M.T.; Hutchison, G.R.; Murray-Rust, P.; Rzepa, H.; Steinbeck, C.; Wegner, J.; Willighagen, E.L.
J. Chem. Inf. Model.,2006, 46(3), 991-998
12. Scalable Partitioning and Exploration of Chemical Spaces using Geometric Hashing
Dutta, D.; Guha, R.; Jurs, P.C.; Chen, T.
J. Chem. Inf. Model.,2006, 46, 321-333
11. Generating, Using and Visualizing Molecular Information in R
Guha, R.
R News,2006, 3(3), 28-33
10. Validation of the CDK Surface Area Routine
Guha, R.
CDK News,2006, 3(1), 5-9
9. Recent Developments of the Chemistry Development Kit (CDK) – An Open-Source Java Library for Chemo- and Bioinformatics
Steinbeck, C.; Hoppe, C.; Kuhn, S.; Floris, M.; Guha, R.; Willighagen, E.L.
Curr. Pharm. Des.,2006, 12, 2110-2120
8. Interpreting Computational Neural Network QSAR Models: A Detailed Interpretation of the Weights and Biases
Guha, R.; Stanton, D.T.; Jurs, P.C.
J. Chem. Inf. Model.,2005, 45, 1109-1121
7. Interpreting Computational Neural Network QSAR Models: A Measure of Descriptor Importance
Guha, R.; Jurs, P.C.
J. Chem. Inf. Model.,2005, 45, 800-806
6. Determining the Validity of a QSAR Model–A Classification Approach
Guha, R.; Jurs, P.C.
J. Chem. Inf. Model.,2005, 45(1), 65-73
5. Using R to Provide Statistical Functionality for QSAR Modeling in CDK to Provide Statistical Functionality for QSAR Modeling in CDK
Guha, R.
CDK News,2005, 2, 7-13
4. Using the CDK as a Backend to R
Guha, R.
CDK News,2005, 2(1), 2-6
3. Development of Linear, Ensemble, and Nonlinear Models for the Prediction and Interpretation of the Biological Activity of a Set of PDGFR Inhibitors.
Guha, R.; Jurs, P.C.
J. Chem. Inf. Comput. Sci.,2004, 44(6), 2179-2189
2. The Development of QSAR Models To Predict and Interpret the Biological Activity of Artemisinin Analogues
Guha, R.; Jurs, P.C.
J. Chem. Inf. Comput. Sci.,2004, 44, 1440-1449
1. Generation of QSAR Sets with a Self-Organizing Map.
Guha, R.; Serra, J.R.; Jurs, P.C.
J. Mol. Graph. Model.,2004, 23(1), 1-14
[…] but it’s also useful to use this data to keep my CV updated or generate a publications page. Since BibDesk can export to Endnote XML format, I put together a simple Python script to process […]