High Content Screens and Multivariate Z’

While contributing to a book chapter on high content screening I came across the problem of characterizing screen quality. In a traditional assay development scenario the Z factor (or Z’) is used as one of the measures of assay performance (using the positive and negative control samples). The definition of Z’ is based on a […]

Cheminformatics and Clam Chowder

The time has come to move again – though, in this case, it’s just a geographic move. From August I’ll be living in Manchester, CT (great cheeseburgers and lovely cycle routes) and will continue to work remotely for NCGC. I’ll be travelling to DC every month or so. The rest of the time I’ll be […]

Accessing High Content Data from R

Over the last few months I’ve been getting involved in the informatics & data mining aspects of high content screening. While I haven’t gotten into image analysis itself (there’s a ton of good code and tools already out there), I’ve been focusing on managing image data and meta-data and asking interesting questions of the voluminuous, […]

ICCS 2011

A few openings are left for the International Conference on Chemical Structures (ICCS) A little less than 40 days left until the 9th International Conference on Chemical Structures (ICCS) starts in Noordwijkerhout, The Netherlands. The conference will focus on the latest scientific and technological developments in cheminformatics and related areas in six plenary sessions: o […]